Certificate of Analysis
| Product Name: | Talazoparib (BMN-673) |
| Catalog Number: | M1732 |
| CAS Number: | 1207456-01-6 |
Physical and Chemical Properties
| Formula: | C19H14F2N6O |
| Molecular Weight: | 380.35 |
| Solubility: | DMSO 25 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.86% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Talazoparib (BMN-673) is a highly potent, orally active PARP1/2 inhibitor.Talazoparib inhibits PARP1 and PARP2 enzyme activity with Kis of 1.2 nM and 0.87 nM, respectively. Talazoparib has antitumor activity. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |