Certificate of Analysis
| Product Name: | Fisogatinib (BLU-554) |
| Catalog Number: | M5237 |
| CAS Number: | 1707289-21-1 |
Physical and Chemical Properties
| Formula: | C24H24Cl2N4O4 |
| Molecular Weight: | 503.38 |
| Solubility: | 100 mg/mL in DMSO |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 98.96% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Fisogatinib (BLU-554) is a potent, highly-selective, oral FGFR4 inhibitor with an IC50 value of 5 nM. The IC50s for FGFR1-3 is 624-2203 nM. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |