Certificate of Analysis

 

Catalog Number: M5272
Product Name: Bioymifi
CAS Number: 1420071-30-2

Physical and Chemical Properties
Formula: C22H12BrN3O4S
Molecular Weight: 494.32
Solubility: 43 mg/mL in DMSO
Long-term Storage: at -20℃
Chemical Structure: Bioymifi Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: Bioymifi, a small-molecule death receptor 5 (DR5) agonist, binds to the extracellular domain(ECD) of DR5 with a Kd of 1.2 μM but showed little binding affinity to the DR4 ECD. It induces DR5 clustering and aggregation, leading to apoptosis.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.