Certificate of Analysis

 

Catalog Number: M5236
Product Name: BI-847325
CAS Number: 1207293-36-4

Physical and Chemical Properties
Formula: C29H28N4O2
Molecular Weight: 464.56
Solubility: 19 mg/mL warmed in DMSO
Long-term Storage: at -20℃
Chemical Structure: BI-847325 Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: BI-847325 is an orally bioavailable, and selective dual MEK/Aurora kinase inhibitor with IC50 of 3 nM, 25 nM, 15 nM, 25 nM, and 4 nM for Xenopus laevis Aurora B, human Aurora A and Aurora C, as well as human MEK1 and MEK2, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.