Certificate of Analysis

 
Product Name: Elimusertib (BAY-1895344)
Catalog Number: M6080
CAS Number: 1876467-74-1
Physical and Chemical Properties
Formula: C20H21N7O
Molecular Weight: 375.43
Solubility: DMSO 12 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Elimusertib (BAY-1895344) Structure
Analytical Data
QC Standard: 98.69%
H-NMR: Consistent with structure
Product Information
Description: Elimusertib (BAY-1895344) is an effective, oral, selective ATR inhibitor with an IC50 value of 7 nM and antitumor activity. Elimusertib (Bay-1895344) showed antitumor activity against A2780 ovarian cancer, PC-3 prostate cancer, LOVO colorectal cancer and REC-1 suite cell lymphoma, and was most sensitive to lymphoma.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.