Certificate of Analysis

 

Catalog Number: M2434
Product Name: BAY 1000394
CAS Number: 1223498-69-8

Physical and Chemical Properties
Formula: C18H21F3N4O3S
Molecular Weight: 430.44
Solubility: DMSO
Long-term Storage: at -20℃
Chemical Structure: BAY 1000394 Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: BAY 1000394 is an orally bioavailable pan-CDK inhibitor for CDK1/2/3/4/7/9 with IC50 of 5-25 nM. It also potently inhibits Aurora A, Clk2, ARK5, FGFR1, Flt3, and JAK2/3. Phase 1/2.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.