Certificate of Analysis

 

Catalog Number: M2424
Product Name: AZD9291
CAS Number: 1421373-65-0

Physical and Chemical Properties
Formula: C28H33N7O2
Molecular Weight: 499.61
Solubility: DMSO
Long-term Storage: at -20℃
Chemical Structure: AZD9291 Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: AZD9291 is an oral, irreversible, and mutant-selective EGFR inhibitor with IC50 of 12.92, 11.44 and 493.8 nM for Exon 19 deletion EGFR, L858R/T790M EGFR, and WT EGFR, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.