Certificate of Analysis

 

Catalog Number: M8914
Product Name: Ceralasertib(AZD6738)
CAS Number: 1352226-88-0

Physical and Chemical Properties
Formula: C20H24N6O2S
Molecular Weight: 412.51
Solubility: DMSO: 70 mg/mL, Ethanol: 40 mg/mL warmed
Storage: at -20°C
Chemical Structure: Ceralasertib(AZD6738) Structure
Analytical Data
HPLC: Shows Min 99.26% purity
H-NMR: Consistent with structure
Product Information
Description: AZD6738 is an orally active, selective ATR kinase inhibitor with an IC50 of 1 nM. AZD6738 inhibits ATR kinase activity and impels cell viability. AZD6738 induces rapid cell death in tumor cells with an ATM gene defect.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.