Certificate of Analysis
| Product Name: | Ceralasertib (AZD6738) |
| Catalog Number: | M8914 |
| CAS Number: | 1352226-88-0 |
Physical and Chemical Properties
| Formula: | C20H24N6O2S |
| Molecular Weight: | 412.51 |
| Solubility: | DMSO: 70 mg/mL; Ethanol: 40 mg/mL warmed |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.26% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Ceralasertib (AZD6738) is an orally active, selective ATR kinase inhibitor with an IC50 of 1 nM. AZD6738 inhibits ATR kinase activity and impels cell viability. AZD6738 induces rapid cell death in tumor cells with an ATM gene defect. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |