Certificate of Analysis

 

Catalog Number: M9581
Product Name: AZD1390
CAS Number: 2089288-03-7

Physical and Chemical Properties
Formula: C27H32FN5O2
Molecular Weight: 477.57
Solubility: DMSO ≥ 15 mg/mL (May need warming)
Storage: at -20°C
Chemical Structure: AZD1390 Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: AZD1390 is currently the most effective and highly selective ATM inhibitor with an IC50 of 0.78 nM, oral activity and the ability to cross the blood-brain barrier. In vivo, AZD1390 combined with radiotherapy effectively inhibited tumor growth.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.