Product Name: | AZD0156 |
Catalog Number: | M10130 |
CAS Number: | 1821428-35-6 |
Formula: | C26H31N5O3 |
Molecular Weight: | 461.56 |
Solubility: | DMSO 2 mg/mL (Need warmed and ultrasonic) |
Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
Chemical Structure: |
QC Standard: | >99.0% |
H-NMR: | Consistent with structure |
Description: | AZD0156 is a potent, selective and orally active ATM inhibitor with an IC50 of 0.58 nM. AZD0156 inhibits ATM mediated signal transduction, prevents DNA damage checkpoint activation, damages DNA damage repair, and induces tumor cell apoptosis. |
Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |