Certificate of Analysis


Catalog Number: M3687
Product Name: AT7519 hydrochloride
CAS Number: 902135-91-5

Physical and Chemical Properties
Formula: C16H18Cl3N5O2
Molecular Weight: 418.71
Solubility: DMSO
Long-term Storage: at -20°C
Chemical Structure: AT7519 hydrochloride Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: AT7519 hydrochloride is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9 with IC50 of 10-210 nM and induces apoptosis in multiple myeloma via GSK-3β activation and RNA polymerase II inhibition.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.