Certificate of Analysis

 

Product Name: ARV-825
Catalog Number: M6206
CAS Number: 1818885-28-7

Physical and Chemical Properties
Formula: C46H47ClN8O9S
Molecular Weight: 923.43
Solubility: DMSO 45 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: ARV-825 Structure
Analytical Data
QC Standard: 99.91%
H-NMR: Consistent with structure
Product Information
Description: ARV-825 is a BRD4 Inhibitor based on PROTAC technology. ARV-825 shows affinity to BD1 and BD2 of BRD4 with Kds of 90 and 28 nM, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.