Certificate of Analysis

 

Product Name: ARRY-520
Catalog Number: M3216
CAS Number: 885060-09-3

Physical and Chemical Properties
Formula: C20H22F2N4O2S
Molecular Weight: 420.48
Solubility: DMSO
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: ARRY-520 Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: ARRY-520 is a potent and selective kinesin spindle protein (KSP) inhibitor with an IC50 of 15 nM for A2780, CP70 and 01-28 cell lines in vitro.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.