Certificate of Analysis

 

Catalog Number: M6217
Product Name: AMD-070
CAS Number: 558447-26-0

Physical and Chemical Properties
Formula: C21H27N5
Molecular Weight: 349.47
Solubility: 10 mM in DMSO
Long-term Storage: at -20°C
Chemical Structure: AMD-070 Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: AMD-070 is a potent and selective antagonist of CXCR4 with an IC50 value of 13 nM in a CXCR4 125I-SDF inhibition binding assay, and inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.