Certificate of Analysis

 

Product Name: AKT inhibitor VIII
Catalog Number: M4988
CAS Number: 612847-09-3

Physical and Chemical Properties
Formula: C34H29N7O
Molecular Weight: 551.64
Solubility: 10 mM in DMSO
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: AKT inhibitor VIII Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: Akt Inhibitor VIII is a cell-permeable quinoxaline compound that has been shown to potently, selectively, allosterically, and reversibly inhibit Akt1, Akt2, and Akt3 activity (IC50 = 58 nM, 210 nM, and 2.12 μM; respectively).
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.