Certificate of Analysis

 

Catalog Number: M6173
Product Name: AHU-377 hemicalcium salt
CAS Number: 1369773-39-6

Physical and Chemical Properties
Formula: C24H28Ca0.5NO5
Molecular Weight: 430.52
Solubility: 54 mg/mL in DMSO
Long-term Storage: at -20°C
Chemical Structure: AHU-377 hemicalcium salt Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: AHU-377 hemicalcium salt is a potent NEP inhibitor with an IC50 of 5 nM. AHU-377 is a component of the heart failure medicine LCZ696.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.