Certificate of Analysis

 

Catalog Number: M5306
Product Name: Acalabrutinib
CAS Number: 1420477-60-6

Physical and Chemical Properties
Formula: C26H23N7O2
Molecular Weight: 465.51
Solubility: 93 mg/mL in DMSO
Long-term Storage: at -20℃
Chemical Structure: Acalabrutinib Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: Acalabrutinib(ACP-196) is a selective second-generation Bruton's tyrosine kinase (BTK) inhibitor, which prevents the activation of the B-cell antigen receptor (BCR) signaling pathway.BMX, and TEC, respectively) and no activity against EGFR.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.