Certificate of Analysis


Catalog Number: M5037
Product Name: A 83-01
CAS Number: 909910-43-6

Physical and Chemical Properties
Formula: C25H19N5S
Molecular Weight: 421.52
Solubility: 50 mM in DMSO
Long-term Storage: at -20°C
Chemical Structure: A 83-01 Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: A 83-01 is a selective inhibitor of TGF-β type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 (IC50 values are 12, 45 and 7.5 nM respectively).
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.