Certificate of Analysis


Catalog Number: M2603
Product Name: GNF-5
CAS Number: 778277-15-9

Physical and Chemical Properties
Formula: C20H17F3N4O3
Molecular Weight: 418.37
Solubility: DMSO
Long-term Storage: at -20°C
Chemical Structure: GNF-5 Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: GNF-5, an analogue of GNF-2 with improved pharmacokinetic properties, is a selective non-ATP competitive inhibitor of Bcr-Abl with an IC50 value of 0.22±0.1 uM (Wild type Abl).
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.